Serie A: Roma vs Inter Milan Odds & Preview
Leaders Inter Head to Rome

Roma Off to Superb Start Under De Rossi
Since sacking Jose Mourinho and replacing him with Daniele De Rossi, Roma are a perfect 3-0. They’ll put their winning streak on the line on Saturday when they host Serie A leaders Inter Milan.
Inter are on a four game winning streak of their own and the Nerazzurri enter the weekend with a four-point lead over second-placed Juventus. As two of the most in form teams in Serie A face off on Saturday, let’s go through the Roma vs Inter Milan odds.
Roma vs Inter Milan Head-to-Head
This is the second match on the Serie A schedule between Roma and Inter Milan in the 2023-24 season. In October, Marcus Thuram scored the game’s only goal as Inter defeated the Giallorossi at the San Siro.
Inter have won six of their last seven games vs Roma overall. Plus, the Nerazzurri have only lost one of their last 14 matches vs Roma, in all competitions.
Resurgent Roma in Top Four Hunt
Lorenzo Pellegrini scored the quickest Serie A goal of the season when he found the net one minute and one second into AS Roma’s match vs Cagliari on Monday. Pellegrini then provided the assist for Paulo Dybala’s goal midway through the first half.
Dybala scored another goal, when he converted a 51st minute penalty and Dean Huijsen sealed the deal with his first-ever Serie A goal. Pellegrini has scored in each of the last three Serie A matches and he’s stepped up under Daniele De Rossi.
Roma’s recent Serie A scores have been quite impressive since Jose Mourinho departed. They’ve outscored their opponents 8-2 over the last three matches and both Pellegrini and Dybala have three goals during that span.
Now, Roma are just one point outside of the top four and are competing for a Champions League spot. However, they’re 0-1-3 vs current Serie A top four teams this season.
The latest Roma vs Inter Milan odds price the Giallorossi as +300 underdogs heading into Saturday’s match. Sardar Azmoun and Evan N’Dicka are currently on international duty.
Still, Azmoun could return depending on Qatar on Wednesday. Meanwhile Leonardo Spinazzola, Chris Smalling and Tammy Abraham are all injured.
Inter Win Derby d’Italia
Inter Milan picked up their most important win of the season on Sunday when they defeated Juventus 1-0. The Derby d’Italia victory meant that Inter Milan, who have a game in hand, moved four points clear of Juventus.
The 57 points Inter have amassed through 22 games is the second-best start in their Serie A history. Inter’s lone goal in the win over Juventus came as Juve’s Federico Gatti accidentally deflected a cross into his own net. Inter have now kept four straight shutouts overall.
Most experts believe Inter will finish on top of the Serie A teams this season.
With 19 goals, Lautaro Martinez leads Serie A in scoring. Yann Sommer has proven to be an excellent g as well. The Swiss keeper, who replaced Andre Onana, has kept a league-leading 14 clean sheets in 22 games. Inter haven’t conceded more than one goal in a Serie A game since early October 2023.
Roma vs Inter Milan Match Analysis & Odds
Inter Milan’s road record in Serie A this season has been superb, at 9-2-0. Meanwhile AS Roma are unbeaten in their last ten home games.
Dybala and Romelu Lukaku have been Roma’s two main offensive threats this season, with 17 goals between them. Inter will need to shut the duo down on Sunday to keep their unbeaten road record intact.
Currently, the Roma vs Inter Milan odds price Inter Milan as -105 favorites as they go for a fifth straight Serie A win. Roma’s recent performances under De Rossi shouldn’t be discounted, as the Giallorossi come in as +300 underdogs. Bettors can take Inter -0.5 at -105 and Roma +0.5 at the same Serie A odds.
Roma haven’t defeated Inter at the Stadio Olimpico since 2016 and a draw is priced at +230. Meanwhile, over two goals sit at -160 odds for this one. Still, Inter have won their last three matches overall by a 1-0 scoreline. The Nerazzurri have also kept consecutive clean sheets vs Roma.
For Serie A betting news, odds analysis, and more, visit Point Spreads Sports Magazine.