Champions League Round of 16: Liverpool vs Real Madrid Betting Preview
Plus Eintracht Frankfurt vs. Napoli on UCL Tuesday

2022 Champions League Final Rematch
The luck, or misfortune, of the draw has brought last year’s Champions League finalists together in the round of 16. Liverpool host Real Madrid on Tuesday in a crucial first leg matchup for both sides. Real Madrid came away with a 1-0 win in the 2022 Champions League but Liverpool will be thinking revenge. Our Liverpool vs Real Madrid betting preview will cover the major odds, statistics and team news from the match. We’ll also take a look at Tuesday’s match between one of the hottest teams in Europe, Napoli, and Eintracht Frankfurt.
Tuesday’s UCL Matches
It doesn’t get much better than this. Last Tuesday, fans got to see EPL season. Playing at home at Anfield in the first leg vs Real Madrid, Liverpool are slight favorites.
In this pick’em, LFC sit at -140 odds to cover, while World Cup winners have averaged 3.8 goals per game during that stretch. Plus, Carlo Ancelotti was able to give Ballon d’Or-winning striker Karim Benzema some crucial rest on Saturday. Benzema has four career goals vs. Liverpool as well. Our Liverpool vs Real Madrid betting preview notes that Real are +185 underdogs for Tuesday’s match, though. Liverpool enter the match as +135 moneyline favorites, while a draw shows +260 odds. These teams have met three times at Anfield over the last 10 years and both teams have won one, along with a draw.
After scoring on Saturday, Liverpool’s Darwin Nunez went off with a shoulder injury and his status is uncertain for Tuesday’s match. He s defender Ibrahima Konate and midfielder Thiago Alcantara on the injury list. Currently, defender Ferland Mendy is injured for Real and midfielder Aurélien Tchouaméni missed Saturday’s match with the flu. Liverpool’s Mo Salah scored seven goals in the group stage and he’ll be key for the Reds here. Meanwhile, Vinicius Jr. and Karim Benzema are the focal points of the Real attack. In a match that’s supposed to be incredibly tight, under three goals sit at -135 odds. On the whole, Real are favorites to qualify for the quarterfinals, as our Liverpool vs. Real Madrid betting preview highlights that they show -135 odds.
Also on Tuesday’s Bundesliga player to reach double-digit goals and assists in the Bundesliga on Saturday. He scored his tenth goal of the season in a 2-0 win over Werder Bremen. Eintracht Frankfurt games have been quite exciting this season, as they’ve averaged two goals per game.
The hosts are half-goal underdogs heading into Tuesday’s match, though. That’s because Napoli have the best record of any team in Europe’s top-five leagues this season. The Partenopei got their 20th win of the season as they defeated Sassuolo 2-0 on Friday. Both parts of the dynamic duo of Khvicha Kvaratskhelia and Victor Osimhen got on the scoresheet. Pundits are quickly running out of superlatives for the Napoli pair, who have been the two best players in Serie A this season.
For Wednesday’s game Napoli -½ displays +120 odds, while Eintracht are -140 favorites to cover the spread. Napoli came in first place in the Group A Europa League final over Rangers last year. Frankfurt come in at +210 odds to pull off an upset victory. They’ve won both of their previous matches vs. Napoli but those were in 1994. A draw certainly wouldn’t be the end of the world for either team and it displays +255 odds.
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